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Flexaril really causes some bad side efffects for me. Skelaxin had no side effects that I noticed, just not right for my condition. I'll give it credit for lowering general muscular tension though." Skelaxin (metaxalone) for Fibromyalgia: Reviews for Metaxalone. Metaxalone. Helped sleep but caused restless legs syndrome." Atropine/diphenoxylate Rating Summary. Atropine / diphenoxylate. I've been taking this medicine for colitis for 3 years and now I can take my daughters out by thousand myself. I'm not running to the bathroom or having accidents, it's wonderful. I do have constipation. So anyone with colitis should try it - I take 2 pills in the morning then 1 every 5 hours everyday, and I'm loving life finally." For Muscle Pain: Reviews for Nabumetone. Nabumetone. My doctor prescribed relafen so far 3 pills and 6 hours im in severe pain" olpid Skelaxin (metaxalone) for Muscle Spasm: Reviews for Metaxalone. Metaxalone. 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